Blueshift Biotechnologies
Now part of MDS Analytical Technologies
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Blueshift is advancing cellular and 3-dimensional colony assays by providing instrumentation that images the entire well, cell by cell, at true high throughput screening rates.
Plate readers measure the total signal for the whole well, or worse, sample only a small area when signal may not be uniformly distributed. Microscopes view only the field-of-view allowed by their objective lens; they must focus and take multiple exposures at multiple filter wheel positions. The IsoCyte™ provides the best of both worlds with true microplate imaging. The entire well, regardless of density, is imaged at micron resolution in four colors simultaneously, without a focus step.
Imaging in the fluorescence anisotropy domain allows discrimination of bound and free label. FRET can be detected by acceptor depolarization even in living cells.
Japanese customers download the IsoCyte™ datasheet here.
Application Includes
- Cell based assays
- Cytotox (ToxCount™)
- Single Cell phospho-protein detection
- Proliferation
- Apoptosis
- Cell cycle
- Protein-protein interactions in living cells
- Hybridoma screening
- Stem cell morphology
- Spot & Bead Arrays in plates